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Staff Information
 
     
  Dr. Arturo Lopez Castel  
 

Post-Doctoral Fellows

 
  Email: arturolopezcastel@hotmail.com  
     
  Research Interest/Responsibility  
     
  DNA repair on trinucleotide repeat instability  
     
  Publications  
     
Axford MM, López-Castel A, Nakamori M, Thornton CA, Pearson CE. Replacement of the myotonic dystrophy type 1 CTG repeat with \'non-CTG repeat\' insertions in specific tissues. Journal of Medical Genetics. 2011 Jul;48(7):438-43.
Tomé S, Panigrahi GB, López Castel A, Foiry L, Melton DW, Gourdon G, Pearson CE. Maternal germline-specific effect of DNA ligase I on CTG/CAG instability. Human Molecular Genetics 2011 Jun 1;20(11):2131-43.
López Castel A, Nakamori M, Thornton CA, Pearson CE. Identification of restriction endonucleases sensitive to 5-cytosine methylation at non-CpG sites, including expanded (CAG)n/(CTG)n repeats. Epigenetics. 2011 Apr;6(4):416-20.
López Castel A, Nakamori M, Thornton CA, Pearson CE. Identification of restriction endonucleases sensitive to 5-cytosine methylation at non-CpG sites, including expanded (CAG)n/(CTG)n repeats. Epigenetics. 2011 Apr;6(4):416-20.
López Castel A, Nakamori M, Tomé S, Chitayat D, Gourdon G, Thornton CA, Pearson CE. Expanded CTG repeat demarcates a boundary for abnormal CpG methylation in myotonic dystrophy patient tissues. Human Molecular Genetics. 2011 Jan 1;20(1):1-15.
Lopez Castel A, Cleary JD, Pearson CE. Repeat instability as the basis for human diseases and as a potential target for therapy. Nature Reviews Molecular Cell Biology. 2010 March; 11(3):165-70
López Castel A, Tomkinson AE, Pearson CE. CTG/CAG repeat instability is modulated by the levels of human DNA ligase I and its interaction with proliferating cell nuclear antigen: a distinction between replication and slipped-DNA repair. Journal of Biological Chemistry. 2009 September; 284(39):26631-45.
     
 
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