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Article
     
 

Lopez Castel A, Cleary JD, Pearson CE. Repeat instability as the basis for human diseases and as a potential target for therapy. Nature Reviews Molecular Cell Biology. 2010 March; 11(3):165-70

 
 
     
     
 

Warby SC, Visscher H, Butland S, Pearson CE, Hayden MR. Response to Falush: a role for cis-element polymorphisms in HD. American Journal of Human Genetics. 2009 December; 85(6):942-5.

 
 
 
     
     
 

López Castel A, Tomkinson AE, Pearson CE. CTG/CAG repeat instability is modulated by the levels of human DNA ligase I and its interaction with proliferating cell nuclear antigen: a distinction between replication and slipped-DNA repair. Journal of Biological Chemistry. 2009 September; 284(39):26631-45.

 
 
     
     
 

Tome S, Holt I, Edelmann W, Morris GE, Munnich A, Pearson CE, Gourdon G. MSH2 ATPase domain mutation affects CTG*CAG repeat instability in transgenic mice. PLoS Genetics. 2009 May; 5(5):e1000482.

 
 
     
     
 

Hagerman KA, Ruan H, Edamura KN, Matsuura T, Pearson CE, Wang Y-H. The ATTCT repeats of spinocerebellar ataxia type 10 display strong nucleosome assembly which is enhanced by repeat interruptions. Gene. 2009 April: 434(1-2):29-34.

 
 
 
     
     
 

Libby RT, Hagerman KA, Pineda VV, Lau R, Cho DH, Baccam SL, Axford MM, Cleary JD, Moore JM, Sopher BL, Tapscott SJ, Filippova GN, Pearson CE, La Spada CTCF cis-regulates trinucleotide repeat instability in an epigenetic manner: a novel basis for mutation hot spot determination. PLoS Genetics. 2008 November; 4(11):e1000257.

 
 
 
     
     
 

Slean MM, Panigrahi GB, Ranum LP, Pearson CE. Mutagenic roles of DNA repair proteins in antibody diversity and disease-associated trinucleotide repeat instability. DNA Repair. 2008 July; 7(7):1135-54.

 
 
 
     
     
 

Christodoulou J, Craig HJ, Walker DC, Weaving LS, Pearson CE, McInnes RR. Deletion hotspot in the argininosuccinate lyase gene: association with topoisomerase II and DNA polymerase alpha sites. Human Mutation. 2006 November; 27(11):1065-71.

 
 
 
     
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